David Hume, 1797-1864, was one of three entrepreneurs who were among the first white trader-hunters to operate in the territories north of Kuruman. Hume, William McLuckie and Robert Scoon had come to South Africa as youths in the Moodie Scottish settlement project of 1817. Having worked off his obligations to the settlement scheme, Hume established a trading post at Kuruman in 1825. From there, he explored in what is now the North West Province and Botswana in search of the elusive Lake Ngami. The three Scots traders enjoyed a good relationship with the Ndebele king Mzilikazi, and hunted elephants in his domain. Over a period of several decades Hume delivered wagonloads of ivory to the Grahamstown market where they were bought by merchants from Europe and Asia. Because of their knowledge of the country and its people, Hume and Scoon offered to guide Andrew Smith's scientific expedition into the Ndebele territory in 1834.
Hume was reputed by contemporaries to have kept a journal of his exploits but this has never being discovered.